Our R&D centre has been designed to accelerate development of innovative processes for niche fermentation-based small and large molecules. With integrated upstream, downstream, and analytical capabilities, we have the right infrastructure to develop and scale up complex biochemical processes at the laboratory stage.
Process development and optimization are carried out using statistically driven Design of Experiments (DoE). AI/ML-based simulation platforms are being leveraged to reduce development timelines and enhance predictive optimization.
Integrated Scale-up Infrastructure
Key Technical Areas
We have in-house capabilities for strain improvement through both targeted and random mutagenesis approaches. Random mutagenesis followed by targeted mutagenesis—post identification of metabolic bottlenecks using bioinformatics tools such as Metabolic Flux Analysis, genomics, and transcriptomics—is employed to develop high-yielding mutant strains with low impurity profiles.
A novel screening assay has been developed to significantly reduce lead identification timelines and accelerate strain selection.
We have in-house capabilities for the design and optimization of recovery and purification processes to achieve high product yield, desired purity levels, and consistent process performance suitable for scale-up and manufacturing transfer.
Downstream Infrastructure
Key Technical Areas
Our analytical laboratory supports development of precise, reliable, and regulatory-compliant testing methodologies.
Analytical Infrastructure
Key Technical Areas